Immune Supports for those with Mast Cell Activation Syndrome and Histamine intolerance: Part 3 Emergency Planning & Targeted Supports

Those of us with Mast Cell Activation Syndrome are likely at higher risk for virus complications. I’m detailing the ways you can be supporting your health right now if you have Mast Cell Activation Syndrome or Histamine Intolerance.

This post is to help you create an Emergency Plan and talks about What To Do if you get sick.

What if your state doesn’t have a shelter in place order yet? I strongly advise everyone with Mast Cell Activation Syndrome to shelter in place.

This means you only leave your home for essentials. And take precautions while you are out to avoid catching this virus.

Also, make sure you are ready with the steps below.

Sourcing Supplements if you have Mast Cell Activation Syndrome or Histamine Intolerance

NOTE: Many people have reached out that they are having trouble sourcing supplements. I have now opened all my private supplement dispensary sources to all Mast Cell 360 blog readers.

US Sources:

(Private clients – you are already getting these discount when you order directly, plus other benefits.)

Fullscript: 15% off store-wide when you create an account and order through this link:

Purchase products through our Fullscript virtual dispensary.

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International Sources:

Go to:

Click Register

Use Registration Code: BO1171

UK and EU:

We have an additional supplement dispensary available for the UK and EU we can open for readers in these areas. To get access to this dispensary, we have to add you individually. You can contact us and let us know you need help getting supplements in the UK or the EU. We will add you to that dispensary. You’ll receive an invitation email from Amrita Nutrition – you’ll need to check your inbox after you are added.

Emerging Research Updates on Pandemic Viruses

I’m posting updates like this regularly on Facebook. I’m also holding FB Lives on Mondays at 2p EDT. Be sure to join the Mast Cell 360 Facebook page here:

Facebook Post Updates:

SARS-CoV-2 Viruses Survives in Air and on Surfaces

A study published in the New England Journal of Medicine on 3/17/20 showed the Sars-CoV-2 virus survives up to 3 hours in the air from aerosol particulates.

What does this mean? You can get sick with COVID-19 by walking through a space where someone who was infected was – up to 3 hours later.

The study also showed SARS-CoV-2 survives 3 days on plastics and stainless steel. The data on cardboard not entirely clear on how long the virus can live. It survives anywhere from 1-3 days on cardboard.

Make sure that you wash your hands thoroughly after touching anything others have touched. I’m letting packages and mail sit for 3 days before handling.

I have a system for packages and mail now. I bring them in and line them up. The most recent packages and mail go to the back. I’m using a hanger as a divider between each day’s deliveries.

After I bring things in, I wash my hands thoroughly. After I bring the 4th’s day deliveries in, I then open the stuff at the front of the line. Because they’ve now sat for 3 days at that point.

Here’s what my system looks like:

Children Can Spread The Virus Even With No Symptoms

A pre-publication release for the medical journal Pediatrics was published online last week. This study of over 2000 Chinese children shows children with no symptoms can transmit the virus.

This is why social distancing for your children is critical. Keep your family safe by staying home unless absolutely necessary.

It takes up to 14 days for someone to show symptoms. Be very cautious about exposures.

Create your Emergency COVID-19 Plan Now – Top Supplements to Have on Hand

I’m still preparing for having COVID-19 at some point. I’m in my 40s. And I definitely don’t want to delay catching this until I’m in my 70s.

But I don’t want to catch it early either. I’m working to delay having COVID-19 until the hospitals are less crowded. And when there is a better understanding of which medications are the best.

I recommend we all have a COVID-19 Emergency plan.

  1. Have your immune boosting supplements on hand NOW that you plan to use if you get sick. You need to order them now because shipping is delayed on many supplements.

These are my top 4 supplement supports right now to have on hand if you get sick.

See more info below for my other top supplement recommendations for those with Mast Cell Activation Syndrome.

Be sure to discuss any new supplements with your healthcare provider. These are immune health supports. They are not meant to treat, cure, or prevent any disease, including COVID-19.

You get 15% off any supplements if you sign up with any of the links below. (Private clients – you are already getting this discount when you order directly, plus other benefits.)

If supplements are out of stock with the links below, try Wellevate.

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Dan shen
– supports cytokine modulation, cell danger response modulation

NeuroFlam – Supports cytokine modulation and Th1/Th2 balance


Th1 Support – Supports cytokine modulation and Th1/Th2 balance

Melatonin – supports immune balance and critical sleep support. IMPORTANT: Use pharmaceutical grade (ie. Pure Encapsulations, Thorne, Douglas Labs, Designs for Health, Integrative Therapeutics, etc.)

Sustained Release (SR) is for nighttime waking. Immediate release is for trouble falling asleep. The last one allows you to start with micro-dosing. Most people use 3-6 mg.

Vitamin C as Sodium Ascorbate – avoid ascorbic acid, which is almost always is from corn fermentation. This product has unfermented ascorbic acid and no corn residues.

Create your Emergency COVID-19 Plan Now – Other Supplements for Consideration

Regarding Vitamin A, D, and Selenium; and regarding all the other supplement fears online.

I’ve been looking extensively into these things. I’m closely following Dr. Yanuck, one of the top Functional Immunologist experts in the world. He really understands the immune system and Mast Cell Activation Syndrome.

I’m concerned people may be getting too deep into the weeds. And losing the big picture with specific biochemistry pathways. Especially when pulling recommendations. For example, with ACE-2 vs. ACE.

These are very complex functions. Much of what I’m seeing online isn’t looking at the big picture here. We have to be asking a lot of questions. Vitamin D does support ACE enzymes. And it supports Th1/Th2 balance. What stage are we in? What are the needs of this person?

Further, Mast Cell Activation is a special case where we are Th2 dominant, which hampers Th1 response. So, we have to look from another angle on these supports.

That said, if the evidence is CLEAR, I am posting updates to recommendations. Please see this post on my retraction on Elderberry:

This is what I’m currently recommending and using in my practice and personally. This is a list for your consideration and research. Please talk to your health care provider.

Everything is in flux. This list can change. But I want to see solid, clear evidence and information. I’m not jumping on bandwagons. But I am following things very closely and reviewing the research.

The major thing I’m doing right now is getting aggressive about Th1/Th2 immune balancing. This is for those with Mast Cell Activation Syndrome and Histamine Intolerance.

That doesn’t mean start everything at once. Still taper up and experiment if you are trying new things. Use good common sense on how slow/fast to taper vs. getting things on board soon.

Additional Supports for Th1/Th2 Balance

You get 15% off any supplements if you sign up with any of the links below. (Private clients – you are already getting this discount when you order directly, plus other benefits.)

If supplements are out of stock with the links below, try Wellevate.

Wellevate Logo

Berberine – also supports Autophagy

Resveratrol from Japanese Knotweed



Quercetin as Iso-quercitrin

Curcumin – stick with short term if you have low DAO

Vitamin D Capsules – contains rice

Vitamin D liquid Option

Vitamin A + Carotenoids – best form for MCAS & HI

Perimine – supports healthy immune and respiratory function

Antimicrobial supports

If you are dealing with significant infections already, bring antimicrobials supports on board slowly.

Argentyn 23 Oral Solution – make sure to use smallest particles like in this product instead of colloidal

Argentyn 23 Nasal Spray – again, this form is much better than colloidal

Monolaurin – research shows it disrupts viral cell wall


Glutathione – use the S-Acetyl-Glutathione Form. Start SLOWLY!

Create your Emergency COVID-19 Plan Now – Make Sure You Have These Devices

  1. Make sure you have a digital thermometer, pulse oximeter, blood pressure cuff on hand.

You want to make sure you have accurate ones. These are some of the best I researched. All the background info on how and why are in this post:

Supporting Health during COVID-19 for those with Mast Cell Activation Syndrome and Histamine intolerance: Part 2 If you Get Sick

SPO2 Pulse Oximeter Oxygen Saturation meter

I have this one by SantaMedical:

In case that one goes out of stock, here are some others that have shown to be reliable:

Blood Pressure Cuff

Omron is a reliable blood pressure cuff manufacturer. I have the 5 series.

Accurate Digital Thermometer

I have a simple one like this style.

2. Consider having a nebulizer, saline, and a fully cleanable humidifier on hand.

More details in this blog post:

Supporting Health during COVID-19 for those with Mast Cell Activation Syndrome and Histamine intolerance: Part 2 If you Get Sick


A nebulizer allows you to breathe a mist into the lungs. This is the one I have:


Saline is used in the nebulizer. You can get straight

Humidifiers are notorious for building in bacteria and mold, so make sure you have one without a filter you can fully clean. I use this one:

Create your Emergency COVID-19 Plan Now – Additional Action Steps 

  1. In case you develop complications
    , make a list of the closest local hospitals covered under your insurance plan. Include addresses and phone numbers.

You want to already have this listed out. So that you are scrambling to find hospitals if you need to go. You don’t want to be doing this if you are having trouble breathing.

  1. Read the CDC Protocol for when you or someone in your household gets sick with COVID-19

This goes into details on how to quarantine in the home. And how to sanitize to protect other family members.

  1. Have a necessities bag packed in case you need to go to the hospital.

It takes 8 days on average between getting sick and developing breathing difficulties. Watch symptoms carefully.

  1. If you have children, discuss childcare arrangements in the event you need to go to the hospital. 

This is something you don’t want to be arranging at the last minute.

5. Make a list now of all medication and food allergies.

Here is a great sheet from the Mastocytosis Society on Emergency Room Protocol you can download.

It also has a QuickList of medications to avoid. And those meds that are generally safe for mast cell disorders. 

Other Blog Posts on COVID-19 for those with Mast Cell Activation Syndrome and Histamine Intolerance

If you missed the last blog posts, I talked about general immune health supports that may help you in these posts:

Coronavirus Facts and Tips for Mast Cell Activation Syndrome and Histamine Intolerance

Supporting Health during COVID-19 for those with Mast Cell Activation Syndrome and Histamine intolerance: Part 1 Essentials

And tips for planning for catching COVID-19 are here:

Supporting Health during COVID-19 for those with Mast Cell Activation Syndrome and Histamine intolerance: Part 2 If you Get Sick  

You can watch the last FB Live here:

FB Live: COVID-19 and Mast Cell Activation Syndrome – Critical Information and Preparedness

And the most recent blog post:

What to do when Supplements are Sold Out during COVID-19

References on Supporting Health during COVID-19 for those with Mast Cell Activation Syndrome and Histamine intolerance

DU Hong-Zhi, HOU Xiao-Ying, MIAO Yu-Huan, HUANG Bi-Sheng, LIU Da-Hui. Traditional Chinese Medicine: an effective treatment for 2019 novel coronavirus pneumonia (NCP) [J]. Chin J Nat Med, 2020, 18(3): 1-5

Keum, Y.-S., Yu, S., Chang, P. P.-J., Yuan, X., Kim, J.-H., Xu, C., … Kong, A.-N. T. (2006). Mechanism of Action of Sulforaphane: Inhibition of p38 Mitogen-Activated Protein Kinase Isoforms Contributing to the Induction of Antioxidant Response Element–Mediated Heme Oxygenase-1 in Human Hepatoma HepG2 Cells. Cancer Research, 66(17), 8804–8813.

M.F. McCarty and J.J. DiNicolantonio, Nutraceuticals have potential for boosting the type 1 interferon response to RNAviruses including including influenze and Coronavirus, Progress in Cardiovascular Diseases. February 12, 2020.

Takamiya, R., Murakami, M., Kajimura, M., Goda, N., Makino, N., Takamiya, Y., … Suematsu, M. (2002). Stabilization of mast cells by heme oxygenase-1: an anti-inflammatory role. American Journal of Physiology-Heart and Circulatory Physiology, 283(3), H861–H870.

Tang, Y., Wang, Z., Huo, C., Guo, X., Yang, G., Wang, M., … Dong, H. (2018). Antiviral effects of Shuanghuanglian injection powder against influenza A virus H5N1 in vitro and in vivo. Microbial Pathogenesis, 121, 318–324.

Zhao, Y., Zhao, Z., Wang, Y., Zhou, Y., Ma, Y., & Zuo, W. (2020). Single-cell RNA expression profiling of ACE2, the putative receptor of Wuhan 2019-nCov. Single-Cell RNA Expression Profiling of ACE2, the Putative Receptor of Wuhan 2019-NCov.

Zhou, Z., Li, X., Liu, J. et al. Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses. Cell Res 25, 39–49 (2015).


  1. Esther Weightman

    NeuroFlam is only available for purchase if recommended. Otherwise, it cannot be added to the cart.

    1. Beth O'Hara

      Thanks for letting me know! It is now recommended for you!

  2. Adina

    Thank you for all this great info but I cannot find Argentyn anywhere, do you have any suggestions?


    What is the different beetween Alpha-Glycosyl Isoquercitrin what you recommend and the other kinds (quercitin dihydrate). I see the dosing is very different. The isoquercitin is a much lower dose. I was taking QBC from Solaray but switched to isoquercitin. Thank you for the great research work and support for our community.

    1. Beth O'Hara

      Hi Beata! I’m so glad it is helpful! Quercetin has low absorbability, and Alpha-Glycosyl Isoquercitrin is better absorbed.

  4. Teresa

    Hi Beth,
    I’ve been taking Pure Encapsulations’ N-Acetyl-L-Cysteine (free form) NAC 900mg 2x/day. Would you not recommend this product?
    Also Amazon is out to the peroxide food grade formulation for the humidifier. What would you recommend using instead?
    Also the “Quick List of medications to avoid” link above, ( ), isn’t working. Would you have a look at it?

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