woman wrapped in blanket

Haywire Mast Cells Block Healing with Mast Cell Activation Syndrome and Histamine Intolerance

In my practice, I see a lot of people with Mast Cell Activation Syndrome who are really struggling. They are reacting to low histamine foods. And even healthy supplements.

They are having trouble with EMFs. And a lot of problems with mold.

What’s going on here?

It’s their Haywire Body.

With a Haywire Body, your Mast Cells will be reacting to everything.

And it’s this Haywire Body and Mast Cells that keep these clients of mine, and maybe even you, stuck.

Here’s an example of someone whose body and mast cells have gone Haywire.

Let’s look at Lanie.

Of course, her name’s been changed for privacy purposes.

But when I first met Lanie, she was struggling with all kinds of sensitivities. And she was really getting fed up. She told me she was feeling absolutely defeated.

Because every time she tried to take her next healing step, she felt like she was taking 2 or even 3 steps back.

One of the things that happened was when she was working with her doctor. The doctor had figured out she had Mast Cell Activation Syndrome.

Which itself is a big deal, because most doctors don’t even know what this condition is.

Her doctor had her start some antihistamine medications. But they made her so sick that she couldn’t go to work for a week.

Her doctor was baffled. And didn’t know what else to do for her. So then she went online. And she started looking into other things she could try.

Like quercetin and curcumin.

But when she took those, she wasn’t able to sleep for 3 nights and she felt really anxious.

She also noticed that she was having more and more trouble with foods.

She even had trouble with low histamine foods, like carrots. They were causing her to get itchy. And she’d start to get flared up. She noticed her chest would get a little tight after eating.

Then she noticed she was having trouble working at the computer.

And it got to where she could hardly go to her church building. Every Sunday her eyes would get really itchy. And she’d get so brain fogged during the service she got nervous to drive home.

She started to think there might be mold in the church building. Which was smart to think about!

But it was so frustrating.

She was even having trouble going to the grocery store. Because so many people were wearing perfumes.

And if she tried to go down the laundry aisle, she’d feel like she might pass out. She just felt like she was reacting to everything.

In the meantime, her doctor had no idea what to do with her. And even acted like maybe she was making these things up.

You see, her doctor had never seen anybody sensitive like this. 

Have you felt like this, too?

Do you have any of these weird sensitivities?

If so, you’re like 99% of the people I see in my practice.

They’re struggling with sensitivities. And they just can’t seem to get over the hump so that they can take their next healing step.

And they’ve told me that this feels devastating.

I really struggled like this too. Every practitioner I saw told me I was the most sensitive person they’d ever seen. And they didn’t know what to do with me.

I started to wonder if I was crazy!

Have you wondered if you were crazy, like Lanie? Or like I did?

Most people think their doctor should know everything about how to get them well. But here’s the problem:

Medical schools, and even naturopathy schools, like I went to, don’t teach healthcare practitioners how to deal with super sensitive people like me. Or like Lanie. Or maybe even you.

And so, unless they’ve been there, doctors just don’t know how to handle these kinds of sensitivities.

Unfortunately, 99% of doctors are missing the #1 biggest step in dealing with Mast Cell Activation Syndrome. 

And without dealing with this #1 step, it’s almost impossible to get all the healing steps on board that you need.

But, here’s the amazing news. If you take this #1 first step, it can literally change your life in a matter of weeks.

Or, for the extremely sensitive people, in a matter of months.

I want you to guess what it is that you have to do first in order to recover your health from Mast Cell Activation Syndrome.

What do you think it is?

What’s the #1 thing you need to do to recover your health from Mast Cell Activation Syndrome?

Do you think it’s a special supplement? Do think it’s the right diet? Do you think it’s just finding the right doctor?

Well, in fact, it’s one thing that hasn’t been looked at through all this time.

It’s your body. And not just any part of your body. It’s how your body is wired. And how your mast cells are wired in your body.

I’ve worked with hundreds and hundreds of people with Mast Cell Activation Syndrome.

And what I’ve found over time is that supporting this wiring is over 50 percent of the healing process when you have Mast Cell Activation Syndrome. So, let’s look at what this means.

You’ve felt this wiring anytime you feel pain. But you also feel it every time you feel love!

Think about the last time you saw a child whom you really enjoy, and who is really special to you, and how it feels like your heart swells.

You also feel this wiring when you feel hungry or thirsty. And you feel it when your muscles get tense. Or feel stressed when you watch something on the news that is out of control. And you don’t know how it’s going to affect you.

So, there are all kinds of ways that this wiring shows up for us. Sometimes it’s more loud and sometimes it’s more quiet.

What happens when you have Mast Cell Activation Syndrome is that it’s wiring has gone “HAYWIRE”.

Brain Electrons Mast Cell 360

See, chemical messages are sent from your brain and other parts of your body to your mast cells.

And also from your mast cells back to your brain and other parts of your body constantly.

This is because your mast cells and your nervous system work together like the guards of your castle gate. And they’re there to sense everything going on around you.

So, that’s whether it’s a new smell, it’s a new food, or it’s a new supplement.

And these chemical messages — this wiring in your body — are talking to your mast cells. Before you can even think about what’s going on.

And if these messages are haywire, like what happens with sensitive people, then your mast cells get these loud danger messages.

And this means that you’re going to react no matter what.

Now, we’re going to look at how to know whether your mast cells are going haywire in the next email. So, make sure to stay tuned for that!

But today, I want to talk about the 3 areas that you have to rewire at the same time if you have Mast Cell Activation Syndrome.

Very few doctors understand the role of the mast cells and how important they are.

But that’s where many, many people working with the MastCell360 process were able to move forward with their health. And be able to move on to their next healing steps.

Because we knew the secrets to working with these 3 major wiring areas that need to be rebalanced, re-regulated, and rewired at the same time.

Now, why do I know about this when other doctors don’t? It’s because my path happened a little bit differently.

So, you may know my story about how I was so sensitive and so sick.

My dream of going to medical school was crushed. When my health completely bottomed out when I was in college.

So, instead of going to medical school, like I had dreamed of, I had to become a chronically ill patient. And learn all this the hard way.

But I got into all kinds of other interesting things along the way: I became a yoga therapist, studying the mind-body connections. And I studied psychology in depth.

And I eventually got my masters in psychology – and did my Master’s Thesis in the area of how the body wiring affects the mast cells.

Then, I went on to get my doctorate in Naturopathy and focused on even more Mast Cell research.

And this information literally changed my life and my health for the better.

This knowledge helped me get my health back so that I could go to get my doctorate and become a naturopath.

And so that I could build Mast Cell 360. So I can help other people who are struggling the way I did.

Let’s get back to these 3 areas that you have to rewire at the same time…

What to Know About the Mast Cell-Body Wiring When You Have Mast Cell Activation Syndrome

Nerves Mast Cell 360

If you have Mast Cell Activation Syndrome, the missing secret of your body is that you need to rewire 3 specific areas of your mast cell-body wiring.

What are these 3 areas?

  • Parasympathetic rebalancing
  • Vagal nerve signaling
  • Limbic system re-regulation

All those fancy science terms can be thought of like this…

Your parasympathetic is the rest and digest wiring or calm and relaxed part of your body. It also controls the healing response.

So, when the parasympathetic is out of whack, it’s nearly impossible to get well!

Next, we have the vagal nerve.

Your vagal nerve signaling is the connection between your second brain (your gut) and your first brain (the one in your skull). It is very important in sleep, calm mood, and healing.

It’s also very important in motility – and can be involved in either constipation or diarrhea.

Then we have the limbic system.

The limbic system is a part of the brain that controls fear and emotions… it’s always on and sending messages before you even have a thought or idea.

It’s a part of your fight or flight response.

Let’s look at these in more depth.

1. Parasympathetic re-balancing for people with Mast Cell Activation Syndrome

The parasympathetic nervous system is an essential part of healing. The parasympathetic nervous system signaling is absolutely critical in healing.

But most of us stay stuck in the opposite of the parasympathetic. This is called the sympathetic nervous system.

This sympathetic nervous system is what keeps you in a state of “fight, flight, or freeze.” It’s what’s active when you feel stressed or under pressure.

As long as you are stuck in sympathetic mode, your body is in an emergency state.

It doesn’t have time or resources to deal with healing. Or lowering inflammation. Or calming mast cells.

If your body thinks it’s under attack your mast cells will be continuously releasing histamine. And lots of other types of inflammation. And it’s going to be impossible to get well.

So, you have to bring the parasympathetic nervous system back into balance.

But in order to do that, we also need to work with the vagus nerve. So, let’s look at it more next.

Heart&Brain Mast Cell 360

2. Vagal nerve signaling for people with Mast Cell Activation Syndrome

The vagus nerve is the nerve that connects your brain with your heart and gut. It’s the longest nerve that runs through your whole body.

The vagus nerve is a super strong anti-inflammatory agent in the body. And calmer of Mast Cells.

And it’s the main activator of the parasympathetic nervous system for the healing response.

It’s also needed for the heart to beat smoothly. And for digestion and bowel movements to happen properly.

That means stimulating the vagus nerve can help balance the parasympathetic system. And improving vagal nerve signaling is one thing we need to do to heal.

When the vagus nerve is doing its job communicating with the body, everything calms down. Including your mast cells.

So we just need to know how to improve vagal nerve signaling.

And the third part of the nervous system to work on is the limbic system. We’ll cover what to know about that next.

3. Limbic system re-regulation for people with Mast Cell Activation Syndrome 

Fear Mast Cell 360

The limbic system is a part of the sympathetic nervous system mentioned earlier. It controls fear and emotions.

When you have constant worry going on, as with a chronic illness, it’s hard to feel safe in your body.

You just never know when something is going to flare up. Or what foods you’re going to be able to eat. Or what supplement to try. Or which doctor or treatment to try next.

Read More: Tips on Creating Your Customized MCAS Flare Up Plan

So, there’s this constant worry in the back of the mind — even if you don’t always feel it.

The body is well aware of every thought and worry. If it senses even a little bit of fear, your limbic system is going to be in overdrive.

And so long as your limbic system is in overdrive… it’s going to be impossible to fully heal.

You can see why it’s so important to rewire these parts of the body.

You can’t heal when your body’s electrical system has gone haywire. You need these 3 parts of your nervous system to work smoothly to support rest and repair.

And you can’t just work on one system. You need a specific way to rewire so that you don’t accidentally make things worse.

If you don’t rewire all 3 of these, you won’t be able to heal fully from Mast Cell Activation Syndrome.

Rewiring all 3 of these is how to stop a Haywire Mast Cell Body.

I’ll explain more in this next section.

Why is specific rewiring so important when you have Mast Cell Activation Syndrome?

Mast Cell 360 Nerves

Well, I learned a lot of this the hard way. And it cost me years of mistakes.

Remember earlier when I talked about becoming a yoga therapist?

I thought at that point that if I just did enough yoga and meditation I would figure out how to heal my body.

And I worked really hard at it. I would do yoga and meditation 2 to 3 hours a day.

But it just didn’t work.

And then I thought if I found the right supplements and the right foods then I would heal my body. And I did that. And worked really hard at it.

And that by itself just didn’t work.

I finally realized through all my studies and looking in depth, that yoga is just going to help the parasympathetic nervous system. But it’s not really going to work for the vagal nerve signaling or the limbic system.

And some forms of yoga can actually make things worse!

And then I learned that the right kind of meditation could help the limbic areas. But it doesn’t rebalance the parasympathetic nervous system or the vagal nerve signaling.

And then there things like certain breathing practices and gargling and singing that could help the vagal nerve signaling. But we don’t do it in the kind of depth that we need.

So the key is to rewire all 3 of these areas at once.

But, how do you do this effectively? Well, there are 2 key parts that you have to include in this process.

Key #1 is to rewire all 3 areas at the same time.

If you miss rewiring one of them, you’re not going to be as successful in healing.

You’ll wonder why it isn’t working. And what it is you’re missing. This is a big mistake I made. I just focused on yoga, meditation, and breathing. And it wasn’t enough.

But, then I learned about the next key in this process which really unlocked my healing.

Key #2 is to use the right techniques for each of the 3 areas of the nervous system. 

The right technique matters. A lot. You might have found out the hard way about how techniques matter already in the areas of supplements or foods. By introducing supplements too quickly. Or by making histamine higher by slow-cooking.

It’s the same with the nervous system. The wrong technique could set off a major reaction.

This doesn’t only happen with foods. It can happen with therapies like yoga or meditation, too.

If you do the wrong kind of yoga, like a Hot Power yoga or Bikram yoga, it could set off your nervous system in a major way.

In fact, you may find yourself in bed for days afterward.

This can also happen with meditation. If you do certain “controlling” meditations, you may think they are helping to calm your mind at that time.

However, the minute you stop, your limbic system will go crazy. That’s because you aren’t rewiring it for normal life.

So, it’s really important to work on all 3 of these areas at the same time. And it’s important to do them safely.

Make sure you only do the Mast Cell approved techniques for each of these.

I’ve seen such a big difference in my practice with these rewiring techniques for HAYWIRE Mast Cells. This is what Lanie did – I worked with her on rewiring all 3 parts of her nervous system.

And guess what! She started to turn the corner in a few weeks. She’d been so stuck in her health. But then she was able to start tolerating more supplements. And foods.

And she could handle going to the grocery store again. It made her mold detox and other healing steps go much more smoothly.

She was smiling and laughing again. And enjoying life with her family.

This is why I want to get this information out to as many people struggling with Mast Cell Activation Syndrome as possible.

Because I’ve seen it work so well for the hundreds of people getting completely stuck with Mast Cell Activation – I’ve seen it help them get to their next healing steps again and again.

That’s why I created this Master Class to show you exactly what to do and where to start.

You can learn more about this rewiring for haywire mast cells in my Mast Cell Nervous System Reboot class right here:


  1. Shelby Aubourg

    Hi Beth,
    Have you ever used any adrenal support supplements for yourself or your clients? How does adaptogens affect the nervous system? Is it always in a positive way or have you seen negative reactions from using them. I believe I have an adrenal issue from my long-term use of topical and oral steroids (haven’t used them in 2 years). I also have MCAS and histamine intolerance.

  2. Christina Silvestros

    Hi Dr. Beth,

    Is there a diet for someone that has mold/sibo?

    Thank you,

  3. Angela

    I did the mast cell nerve rewiring course recently. It suggested accupressure points. I did them and while most were fine, the ones on my cheekbones (parallel with pupil) were horrifically painful. Even just having touched them for like 3 seconds, probably for 10 minutes afterwards I felt seriously like someone had hit my cheekbones with a hammer. The one on my hand near thumb had a similar but lesser lasting reaction.

    I woke up this morning and my cheekbones hurts so bad and my upper jaw ached so much It feels like I clenched my teeth severely all night. All my upper teeth are aching and painful today like they are on the verge of all falling out. My sinuses are whistle clear. I’m not sick. I can’t get rid of the terrible aching cheekbones, jaw bones and teeth. Now the skin on my face feels like it is burning (with MCAS I experience burning skin elsewhere here and there from time to time) as the day wears on.

    I thought this was supposed to be calming to the nervous system. I know it is not your fault. But I am very intrigued if this happens to some crazy sensitive patients? Is this a “normal” MCAS response reaction to accupressure in some people? I have been googling and googling online and all I can see is how wonderful accupressure is to resolve all sorts of nervous issues, tensions, etc….rather than trigger a mast cell meltdown. I do have TMJ but never this bad, but just touching my joint on that side feels like I chewed iron bolts for hours straight.

    I know Beth says do what you only can do and don’t push it. But I wouldn’t say I was overdoing anything….just really experimenting, not going overboard. Just wondering if you have ever seen this happen in patients trying this. It seems the reaction was sudden and immediate and way overboard.

    Does this point to a particular nerve which is causing problems? Beth said accupressure points connect to different nerves in the body.


    1. Suz, Mast Cell 360 Team

      Hi Angela,
      I’m so sorry to hear this happened. This is very unusual, even in sensitive people. I’d get this checked out by an ENT to make sure something bigger isn’t going on. I would work on other modalities for your nervous system, use any mast cell supporting supplements or meds you know you can take, and make sure you aren’t exposed to mold. If things feel calmed down in the future (like very calmed down), then you might retry with some very light brushing – like a feather – on those points or even just do it “off body” where you hold above the point without touching the skin. Hope you’re feeling better soon.

  4. Debbie

    Is there an adrenal supplement you would recommend that includes ashwagandha? I’ve been taking a combination adrenal supplement that has eleuthero, ashwagandha, rhodiola, asian ginseng, licorice, tyrosine, vit c plus some other ingredients. I stopped it because I suspected some of the ingredients were affecting high histamine in my body. the supplement did help with fatigue and now that I’m not taking it the fatigue has gotten worse again.

    1. Suz, Mast Cell 360 Team

      Hi Debbie,
      I don’t recommend ashwagandha because it is a lectin. Rhodiolo and Vitamin C is usually ok, but it depends on case. We can’t say what will be right for you without knowing your history. These are the two we use here in the practice. You’ll want to look into these on your own to see if they might be right for you. Please be sure to talk with your doctor or practitioner with questions or concerns. If you decide these are right for you, start very slowly (we usually say with just sprinkles or drops) and very gradually build up if you are able to tolerate them.


      and Vitamin C:

      Suz, MC360

  5. Carrie Burbey

    I’m looking for water purification for shower and bath. Any suggestions?

  6. Robin Lillian

    Can you have MCAS if you can tolerate most supplements and don’t have multiple chemical sensitivities?

    1. Suz, Mast Cell 360 Team

      Yes. MCAS shows up differently for each person.

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