Functional Genetic Factors in Mast Cell Activation Syndrome
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Find out the underlying genetic issues that commonly cause Mast Cell Activation Syndrome and get a better understanding which ones are affecting you or your clients.

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Master Class on Functional Genetic Factors in
Mast Cell Activation Syndrome

Hi, I’m Beth O’Hara, Functional Naturopath and Functional Genetic Analyst. I’m also a Mast Cell Activation Syndrome survivor. Uncovering my own genetic triggers was one of the major keys in unlocking my Mast Cell health mysteries. 

Mast Cell Activation Syndrome affects between 9-17% of the general population. And it affects over 50% of the chronically ill population. Mast Cell Activation Syndrome is one of the most under-recognized and under-diagnosed conditions. Functional genetic factors in Mast Cell Activation Syndrome number in the thousands.

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I’ve created this Master Class on Functional Genetic Factors in Mast Cell Activation Syndrome to help you learn about genetic triggers in Mast Cell Activation Syndrome. In this Master Class, you will learn about:

  • Genetic Expression in Mast Cell Activation Syndrome
  • Histamine Degrading Pathways
  • The role of Methylation in Histamine Breakdown
  • The role of Autophagy and MTOR in Mast Cell Activation Syndrome
  • How Phase I, II, and III Detoxification affect Mast Cell Activation
  • NADPH Oxidase – a crucial enzyme in Mast Cell Dysregulation
  • The roles of Oxalates and Glutamates in Mast Cell Activation Syndrome

Throughout this Master Class, I’ll be discussing real-world Mast Cell Activation Syndrome cases and the role of genetics in these cases. 

Are you interested in working with a practitioner 1:1?  

If so, you can apply to see if the Mast Cell 360 Practice is a good fit for you. Click the button below: 

“Before I met Beth, I could not get rid of chronic Lyme symptoms and I was having so many reactions to foods and environmental insults. I felt like I’d never get better. I didn’t understand Mast Cell Activation Syndrome (MCAS) and Histamine Intolerance so I was mainly going after Lyme and heavy metal toxicity symptoms using herbs, homeopathics and supplements. Turns out I was taking and eating a lot of things (like ferments) that kept me from getting better. I believe now that the Lyme had no longer been an issue for years, and it was actually undiagnosed MCAS as well as underlying issues caused my metals, molds and genetic mutations.

I really wanted to work with someone who understood genetic analysis and how that related to the symptoms I was having. After serendipitously speaking with one of Beth’s other clients I suspected I could have MCAS and wanted to address it.

Through working with Beth, I now understand my genetic issues. I know how to take care of myself around food and environmental triggers. And I now know that I still have heavy metal and mold toxicity to work on to feel 100%.

Working with Beth’s Mast Cell 360 program has helped me understand MCAS and how oxalates and lectins cause flares for me. I also understand what works and doesn’t work for my body, given my genetics. I am now a new person. I can imagine my future again and I’m taking steps to rebuild my life.

The first thing I noticed were less mast cell reactions. I had been having constant burning mouth and red neck. I even broke into hives when I showered. This went away after about 8 months. My brain fog is nonexistent most of the time (that was a huge issue I was dealing with). My neurological inflammation improved, joint pain improved, and my energy has massively improved. My anxiety and agoraphobia are gone too. My life has changed to nearly normal. I still have improvements to continue to make, but I think I mostly need to increase my stamina which has been on hold for 8 years.

When I had my first session with Beth, she believed it would take me about 18 months to really feel better. She was right on target! It’s been 16 months and the relief from my symptoms has exponentially grown in the last few months. I will be forever grateful to Beth for putting me on the road to wellness.”

-Joy E.
Joy E.

“Metamorphosis. This word best describes my experience with Beth O’Hara. In the two years we have been working together, she has made a tremendous impact on my life. When I first came to Beth, I was struggling every day with MCAS and the accompanying excruciating fibromyalgia pain, migraines, joint pain, severe fatigue, depression, anxiety, panic attacks, and sinus problems. I also have Type 2 diabetes. Just getting the dishwasher loaded was impossible and I wasn’t able to drive myself. I had seen dozens of doctors and been on every medication imaginable, but I seemed to continue to get worse.

Beth recognized the food triggers that were causing my symptoms and helped me make changes to how I was eating. She also reviewed my genetics and explained in clear language that I could easily understand how my genes might be affecting my health and helped me with action steps on how to address genetic variants. With these changes, my fibromyalgia and rheumatoid arthritis have decreased tremendously and my sinusitis has almost ceased to exist. My A1C is even down!

My Mast Cell Activation Syndrome is much better managed, and I’m able to drive and even enjoy life again. Life-changing. . .”

-Kathy H.
Kathy H.

“Beth has a keen ability to know when introduce the next level or process and she has a wealth of knowledge and the tools to fit my individual needs, she knew exactly when to bring them on board. With her guidance, we incorporated supplements and food changes based on my DNA, along with changes I needed to make in my life to support my health, both body and mind. My histamine issues and inflammation are significantly better, and I am enjoying life in a whole new way.”

-Beulah H.
Beulah H.

“When I was diagnosed with colorectal cancer, I knew I had to make some changes in my life. After going through radiation, chemo, and surgery, I decided it was time to take charge of my health. I knew I had histamine sensitivity, however, the information available was overwhelming and I was not sure how to figure out what was right for me. I turned to Beth O’Hara to see how genetic testing and personalized supplementation could help. Beth was able to analyze the DNA test results and help me to figure out the best foods and supplements for a healthy lifestyle for me.

Beth has been a wonderful help in navigating through the healing process. I feel so much better! Her vast knowledge, empathy, and calming demeanor have been such a blessing!”

-Tricia B.
Tricia B.

“I highly recommend Beth. She is a true health detective. She combines genetic analysis, symptoms and medical test interpretation and figures out what foods, supplements and mind/body approaches are best. She understands how things work in the body and that everyone is different. She offers a very personalized approached at a very reasonable cost. There are many people out there doing genetics, but Beth’s approach makes her far better than the rest. She has succeeded where other doctors have failed.”

-Vicki Y.

“I went to see Beth when I was having several areas of health concerns and wanted more holistic answers. She asked really great questions and listened with an open mind and an open heart, which helped her get to the bottom of what was causing my health issues. Beth can integrate information from DNA reports, lab results, discussions, observations, her knowledge of how the body works, nutrition, and lifestyle to provide individualized solutions that work for me. My histamine levels are way down, and I’m feeling much better after working with Beth. I recommend her for anyone who is experiencing health concerns and would like a holistic approach that addresses the whole person!”

-Liz J.

“My experience has been that her knowledge of individual genetic tendencies allows her to pinpoint contributing factors in many complex health issues, particularly those in which histamine issues and inflammation were a contributing factor.  Beth has also been an invaluable resource for me due to her extensive network of competent and skilled practitioners who, like her, are on the cutting edge of new ways to be healthy and whole in mind and body. I have seen significant improvements in my energy, neurotransmitter balance, and sleep and have even been able to come off some of my medications.”

-Alan H.

“I came to Beth in chronic pain and fatigue that began with a shoulder injury that was not healing. I was barely sleeping at night and my body was full of inflammation. I’d been through a round of traditional PT and believed I was eating healthily, but I was just not getting better no matter what I tried. With Beth’s guidance, I began to recognize and understand MCAS and other underlying hyper mobility issues that I had. I began the MastCell360 protocol, got the right testing and began taking supplements that were gradually bringing me back into balance.

The supplement recommendations were also a game-changer for me, and I was finally able to break out of my long cycle of pain and inflammation. Beth truly is on the cutting edge of this field, and I am so grateful to her for it. I’m still healing, but it’s been such a huge transformation that I can barely even remember those days of chronic pain, sleep deprivation and hopelessness now.”

-Gail T.
Gail T.

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