How To Detox Your Body from Mold with MCAS
Learning how to detox your body from mold was a game-changer for my Mast Cell Activation Syndrome and Histamine Intolerance.
In fact, Mold Toxicity is the #1 Mast Cell Trigger I see in my practice. 99% of people in my practice have Mold Toxicity.
When I was really sick with Mold Toxicity, I struggled to just make it through the day.
For a long time, it negatively affected my personal life and my work life.
Truly, I was just barely hanging on.
My health issues were affecting my life in so many ways.
I couldn’t socialize because lights and sounds were painful.
I had so many food intolerances that eating out was a no-go.
There were years when I had to sleep 12-14 hours a night just to function at a low level. Even then, I still struggled to get anything done during the day.
My brain fog made it difficult to concentrate on anything. And I had chronic fatigue which exhausted me with even the smallest tasks.
But when I figured out how to detox my body from mold, I started being able to think more clearly again. I started getting my brain back! And my energy started coming back, too.
I was able to handle talking to people again. Lights didn’t bother me so much. I started tolerating more foods.
In short, I got my life back!
I went from struggling just to get by to building my Mast Cell 360 practice.
I want you to get your life back, too! I want you to be able to get your health back.
I want you to enjoy your life. I want you to be able to follow your dreams.
But mold toxins may be holding you back.
Keep reading to learn more about how to detox your body from mold.
You’ll learn about:
- Why mold toxins (mycotoxins) are a big trigger in Mast Cell Activation Syndrome
- Other conditions mold may be preventing you from healing from
- How mold detox is different for those with Mast Cell Activation Syndrome
- The right order for how to detox your body from mold
- The best binders for Mast Cell Activation Syndrome
- The 7 stages of how to detox your body from mold in Mast Cell Activation Syndrome
- Considerations for how to work with each of the 7 stages of how to detox your body from mold
So How Do You Know If You Are Dealing with Mold Toxicity?
Start with this question: Have you had mold exposure?
Toxic mold exposure can come from anywhere with moisture — from wet basements to walls with water damage to unchecked crawlspaces.
And even exposure from years ago can still affect your health conditions if it was never addressed!
For more about what mold toxins are and mold testing, be sure to read:
Next, let’s look at why mold toxins are a big trigger from Mast Cell Activation.
Why Mold Toxicity is Such a Big Trigger in Mast Cell Activation Syndrome
Some types of mold release toxins called mycotoxins. These mycotoxins are invisible gases. You can breathe these in from the air without even knowing it.
Once in your body, these mycotoxins can spread to all the tissues in your body.
Mycotoxins disrupt every system in your body including your nervous system and immune system. Mycotoxins also disrupt your detox systems making it harder to get rid of them.
If you are continually being exposed to mold in your environment, you can continue to get these mycotoxins in your body. And you’ll continue to see the negative effects of these toxins if your body isn’t detoxing them naturally. They’ll build up and cause a ton of issues.
This buildup of mold toxins is called Mold Toxicity. If you are exposed to a lot of mold, you can also breathe in mold spores.
Mold spores are how mold reproduces. Think of it like a seed.
Once these spores get inside you, they can take hold, like a seed, and start to grow if your body doesn’t attack it like it should.
When mold starts growing inside you, it is called Mold Colonization.
And remember how we said mycotoxins disrupt the immune system? This means that those mycotoxins make it harder for your body to stop mold from growing inside you.
Yes, these spores can live and grow and reproduce using your body as a food source for itself! And the mold that grows in your body will release mycotoxins, too.
If you’ve only been exposed to mold for a short amount of time, you may have Mold Toxicity, but no mold growing in you yet.
But about 70% of adults exposed to mold have Mold Colonization. And if you have Mold Colonization, you can be out of a moldy environment, but you still have to get rid of mold growing inside you.
This is because that mold inside you will keep releasing more mold toxins. And the mold growing inside you breaks down your tissues to feed on your nutrients – Yikes!
And Mold Toxicity can lead to:
- Mast Cell Activation
- Immune dysregulation
- Parasympathetic and Vagus Nerve disruptions
- Methylation dysregulation
- Hormone dysregulation
- Low immunity – inability to fight off infections
- Gut disruptions
And here’s another way Mold Toxicity may be holding your health back.
Because mold disrupts your immune system, it is very hard to get the following conditions in check until you address mold:
- Chronic EBV infections
- Chronic Lyme and coinfections
- SIBO and other gut issues
- Hormone imbalances
- Sleep issues
- Mast Cell Activation Syndrome
- Histamine Intolerance
- Salicylate Intolerance
- Subclinical Porphyria
You’ll notice that Mast Cell Activation Syndrome and Histamine Intolerance are in the list above.
I see Mold Toxicity as the root cause of Mast Cell Activation Syndrome in 99% of my clients.
You likely know that mast cells are a part of your immune system. And mold is a major disruptor of the immune system…
Mold messes up how your mast cells receive and respond to different signals. And that can lead to overly-responsive mast cells.
And here’s another way mold is hurting you. Mold triggers something called the cell danger response.
Let’s look at that next.
Cell Danger Response
Your body uses cell danger response to protect your cells and you from harm.
Cell danger response can be triggered by:
- chronic infections from viruses and bacteria
- other toxins (like chemicals, heavy metals)
- chronic stress
You just read that mold can trick your immune system.
Viruses and bacteria can hijack many processes in your body, too. All invaders do this to survive (at your expense!)
To fight back, the cell danger response starts to:
- Reduce methylation
- Lower Vitamin D levels
- Slow down methylation
- Harden the cell membrane
- Increase inflammation
- Increase histamine
- Increase mast cell activation
- Slow toxic metal excretion
- Alter the heme pathway
- Change the gut balance (contributing to leaky gut)
The result is inflammation, immune reactions, a breakdown of tissues, and an all-around state of emergency.
This is all to prevent the mold, viruses, bacteria, and other toxins from killing you.
Now, all of this can cause mast cell reactions, too.
And you might be thinking the immediate solution is to take a bunch of medications to knock out your mast cell and histamine response.
It’s true that medications can be helpful for many people when used correctly.
Some low-level medications often ease challenging symptoms and allow you to finally tolerate detoxing.
The problem comes if all you do is take medications.
If you don’t handle the root causes, you can get worse in the long run. You’ll knock down your mast cell defenses, and the mold, viruses and bacteria will have free reign.
This is why it’s very important to address the root causes underlying your mast cell dysregulation.
So, how should you consider addressing mold if you have Mast Cell Activation Syndrome?
Great question. You may need to approach detox differently if you have MCAS or other sensitivities.
Some of the other protocols may be too aggressive for you.
But I’ve got a method for how to detox your body from mold for you that has worked well for me and many of my clients. I’ll share these steps with you next.
How to Detox Your Body from Mold Differently with Mast Cell Activation Syndrome
If possible, the first step to addressing mold toxins is to reduce your mold exposure.
In some cases, this may mean moving.
But in other cases, it may mean remediating your home or work environment. Remediation means getting rid of harmful mold growth.
You can learn more about remediation and environmental mold (particularly indoor mold) in this article: Top Tips on Environmental Mold.
Getting out of mold is huge. Without new exposure, you can really tackle Mold Toxicity head-on.
However, I know that not everyone will be able to get out of mold right away.
But even if you can’t move or remediate just yet, you can still start working on detoxing your body from mold.
When you start to detoxify, you can still make improvements. It may just take a little longer to reach that fully recovered mark.
Keep reading for action steps to consider for how to detox your body from mold. But first, let’s briefly look at what usually doesn’t work.
Aggressive Protocols, Die-Off, and Herx Reactions
Practitioners will often start out by putting people with chronic illness on some type of detox and antimicrobial (like antibiotics and anti-fungals) protocol.
This makes sense sometimes since chronic illness is often seen with parasites, Lyme disease, or Mold Toxicity.
But one of the major issues I see is that those protocols are often done too aggressively for people with Mast Cell Activation Syndrome.
Often, my clients have really bad reactions from these aggressive types of detox and antimicrobial protocols.
These reactions can be from several different detox mistakes.
For instance, I often see people put on antimicrobials without any binders on board first.
Another mistake is not addressing constipation first.
Why would those be mistakes? Think about it like this.
Toxins are trash.
You have to first collect the trash (binders) and then remove the trash (bowel movements).
If you don’t collect the trash, it stinks up your space, right? That’s not good.
And if you just collect the trash in a bag but you don’t take it to the curb on trash day, the trash stinks up your house, too, right?
So, first, collect the trash (binders) and then make sure the trash collector is coming (regular elimination)! 😀
I’ll talk about elimination more in a bit, but first…
Speaking of toxins as trash…If you have Mold Colonization, you’ll get more trash (toxins) when you start to kill off these microorganisms.
When you start killing off these microorganisms (like mold), they can release more toxins as they die off.
For example, when you kill off a pathogen like mold with antifungals, more mold toxins are then released.
Killing protocols can lead to what’s called a die-off or Herx reaction. This is just the name for how your body responds to the toxins released when microorganisms in your body are dying off (thus called die-off).
Die-off or Herx reactions can often result in an inflammatory mast cell response.
And with die-off reactions, you may end up with symptoms like:
- body aches
That’s just to name a few.
Many times, people are told to push through a Die-off or Herx reaction. But that’s a bad idea when you have Mast Cell Activation Syndrome.
These Die-off or Herx reactions are an indication that your body is in a toxic state. And the side-effect of pushing through this can be months of mast cell flares.
So, let’s look at how to detox your body from mold differently if you have Mast Cell Activation Syndrome.
The 7 Stages of How to Detox Your Body from Mold in Mast Cell Activation Syndrome
Detoxification protocols must be done in the right order for those with Mast Cell Activation Syndrome.
In the paragraphs that follow, I’ll lay out steps that will help guide you in doing a mold detox protocol in the right order.
However, these protocols need to be tailored specifically for your case, including your:
- specific mold toxins
- detox pathways
- ability to eliminate toxins
You can use this information to get started. But you may find that you want the help of an experienced healthcare practitioner who specializes in how to detox your body from mold.
Always talk with your healthcare provider with any questions or concerns.
I’ve broken down this protocol into 7 stages. Again, with MCAS and Mold Toxicity, the order you do these stages in is very important.
After working with hundreds of people with Mold Toxicity, as well as addressing it for myself, I’ve found these 7 stages to be most effective if you also have Mast Cell Activation Syndrome and corresponding issues like Histamine Intolerance.
I want to thank Dr. Neil Nathan who’s been a huge contributor to this area of study on Mold Toxicity and his contributions to teaching practitioners how to work with those with Mast Cell Activation Syndrome and significant sensitivities.
This information came from an extensive research project on the Detoxification of Mold Toxins by Neil Nathan, MD; Emily Givler, DCS; Joe Mather, MD; and me.
Here are the 7 stages of how to detox your body from mold in Mast Cell Activation Syndrome:
1. Identify which Mycotoxins You Are Dealing With
It’s important to know which specific toxins you’re dealing with. You can find this out through testing.
In my practice, I use two urine lab tests side by side: The Great Plains Mycotoxin test and the RealTime Mycotoxin test.
The Great Plains Mycotoxin testing method seems to be better at detecting ochratoxins, mycophenolic acid, and citrinin.
The RealTime Mycotoxin test is more sensitive for trichothecenes, gliotoxins, and aflatoxins.
The two tests complement each other. So, when they are used together, we can get a more complete picture of the molds and mycotoxins affecting the body.
If you can only afford one, get RealTime because it has fewer false negatives.
Let’s look at both of these tests in more detail.
Great Plains Mycotoxin Test
Here’s a sample of a Great Plains Mycotoxin test:
If the Great Plains results come back low, don’t let this fool you. You can learn about how to understand the results in the MC360TM Precision Mold Detox
Here is where you can get the test:
This test checks for 11 different types of mycotoxins coming from 40 species of mold. The mycotoxins tested include the following:
Mold Toxins Being Tested:
- Aflatoxin M1 (AFM1)
- Ochratoxin A (OTA)
- Sterigmatocystin (STG)
- Roridin E
- Verrucarin A
- Enniatin B1
- Mycophenolic Acid
- Chaetoglobosin A
Fasting is not required and the turnaround time is usually 21 days.
RealTime Mycotoxin Panel
Here’s a sample of a RealTime Mycotoxin Panel:
Certain States are “Direct Access” – and give you better pricing: Alaska, Arizona, Arkansas, Delaware, District of Columbia, Indiana, Iowa, Kansas, Louisiana, Minnesota, Mississippi, Missouri, Montana, Nebraska, New Mexico, North Carolina, North Dakota, Ohio, Oklahoma, South Dakota, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin
International or in a Direct Access State?
In the US but not a Direct Access State?
This test checks for the following mold toxins:
- Satratoxin G
- Satratoxin H
- Isosatratoxin F
- Roridin A
- Roridin E
- Roridin H
- Roridin L-2
- Verrucarin A
- Verrucarin J
- Aflatoxin B1
- Aflatoxin B2
- Aflatoxin G1
- Aflatoxin G2
Fasting is not required and the turnaround time is usually 7-10 business days.
Why is this important? Different mycotoxins require different supplements or binders.
For example, aspergillus releases the mycotoxins called aflatoxins, citrinin, gliotoxin, ochratoxin, and sterigmatocystin.
Another species of mold is called Fusarium. It produces the mycotoxins trichothecenes and zearalenone.
This means there is no 1-size-fits-all mold detox protocol.
You need to know what mycotoxins you have so you can pair the right supplements to get rid of it. I call this Precision Detox.
While you are waiting for your test results, you can go ahead and start with Step 2 of how to detox your body from mold.
2. Nervous System Supports
Mold toxins cause vagal nerve, parasympathetic, and limbic system disruptions.
You may need multiple types of modalities to support your nervous system. This is the single most important beginning phase. If this phase is skipped, the mold detox protocol will not go as well or be as effective.
This is because mold toxins significantly affect the nervous system. And if the nervous system is dysregulated, you will likely have trouble getting supplements on board due to overly-responsive mast cells.
You can support your nervous system from three different angles:
- Active/Conscious Support
- Passive Receptive Support
- Structural Support
Here are some of the modalities I use for each of these different angles.
I love their Active/Conscious support limbic training. This program is much more effective than meditation and breathing alone. This program also retrains your brain and nervous system.
What many of my clients (and me too!) love about this program is that it isn’t a strict, regimented approach.
They made Passive/Receptive support easy so you can relax and listen to their programs.
There are wonderful exercises for Structural Vagal Nerve Supports in this book. He gives you baby steps in Part 2 to try.
This is a form of structural support. Craniosacral therapy (CST) is a gentle hands-on technique that can relieve tension in the central nervous system.
Work with a practitioner who can give you this hands-on therapy modality. Keeping this appointment is my favorite time of the month!
Once you’ve gotten your nervous system supports in place, next, you want to be sure your body is prepared to get rid of toxins effectively.
Let’s look at that next.
3. Elimination – Addressing Constipation and Water Consumption
Remember how you read that one mistake I’ve seen in other protocols is starting detox without addressing constipation first? That’s all about the importance of elimination.
The body eliminates toxins through both the urine and the stool. That’s why it’s extremely important to drink enough water and to have regular daily bowel movements.
- During detoxification you should drink at least half your body weight in ounces. For example, if you weigh 150lbs, you’ll want to drink 75 ounces of water a day.
- Any drinks with caffeine won’t count toward that goal. Caffeine actually uses up water to be processed.
- You can count pure water or herbal teas toward your goal.
Addressing constipation as needed
- Parasym Plus™ can be helpful for constipation from vagal nerve issues. Use my coupon code mast360 for 10% off.
- Magnesium Oxide works as a natural laxative. It’s a good option for sensitive people. Get 15% off of all supplements in the Fullscript store when registering with my link above.
You can also get 15% off anything at Fullscript anytime when you register with this link. If you don’t have an account already, it’s free and you just enter your email address to sign up. It never costs you any more, but your Fullscript purchase helps support Mast Cell 360 free online resources.
Once you are having regular bowel movements and drinking plenty of water, next you can consider adding some mast cell supporting supplements.
4. Supporting Mast Cells with Supplements
A very important part of detoxing with Mast Cell Activation Syndrome is the concept of microdosing.
Microdosing means when you are onboarding supplements, you want to do so slowly and just a little bit at a time.
If you have Mast Cell Activation Syndrome, you want to start any type of supplement in very tiny quantities. I like to say start with drops or sprinkles.
If you are using a powdered supplement, consider starting with just a pinch.
And if your supplement comes in a capsule, you can often break it open. You can take just a portion of the contents. It’s often better to start this small rather than with a whole or even half a capsule.
This is for 2 reasons:
- A person with Mast Cell Activation Syndrome can react to anything. So, if you are going to react, your reaction to a sprinkle likely won’t be as bad as your reaction to a whole capsule.
- When mast cells get dysregulated, like in Mold Toxicity, they will start firing at anything new. Starting small can help you get the new supplement on board without the mast cells targeting it as an enemy.
So, if you’re adding in a new supplement, it’s often much more effective to start with tiny quantities, like a sprinkle in a glass of water. You can slowly build from there, as tolerated.
Remember, if you aren’t tolerating supplements yet, you may need to work on your limbic and vagal systems.
Also, be sure to check for environmental triggers like mold and EMFs.
But if you are ready to take supplements, here’s why they can be helpful at this stage.
Mast cells become so dysregulated from mold toxins. This is what contributes to all the Mast Cell Activation-type symptoms in Mold Toxicity.
So, you can support your mast cells with nervous system work and supplements.
These supports can help calm and stabilize the mast cells.
You can learn more about some of these supplements in the Top 8 Mast Cell Supporting Supplements Master Class here:
This should help you with mast cell reactions as well as help you onboard binders.
Once you’ve worked on the nervous system, optimized elimination, and have given the mast cells some support, then you can move into the binder phase. That’s next.
5. Targeted Binders
Binders help remove toxins from your body. They attach to the toxins to help prevent them from getting reabsorbed. And they can help your body eliminate these toxins better, too.
Certain binders bind different types of mold toxins better than others.
This is why it’s really important to make sure that you test to know what mycotoxins you are dealing with.
Below are some of the more common toxins along with their binders. Remember, when you start anything new you want to microdose!
Saccharomyces Boulardii is a probiotic. It helps with the microbiome of your gut.
It also binds:
Bentonite Clay binds:
- Enniatin B
Activated Charcoal binds:
- Enniatin B
- Enniatin B
- T2 trichothecene
- Bile binders that may bind others
L. Rhamnosus binds:
It’s important to note that zeolite will also bind metals. So, you have to be careful with it. I always recommend adding zeolite after other binders are on board.
And I recommend starting everything slowly.
If you start feeling worse, back off. This is because if you start to have a “die-off” reaction, that’s an indication that you’re moving into a toxic state.
Your body is overwhelmed with more toxins than it can handle and you’re having a mast cell flare.
Those mast cell flares can turn into a cascade that goes on for several weeks or months. So, you want to go slowly.
My motto in any type of detox in Mast Cell Activation Syndrome is, “Slow is fast, but fast will be slow.”
What does that mean? If you try to go too fast, it’s going to slow down your progress because you can set yourself back several months with potential reactions.
Another thing to keep in mind with binders is that they don’t necessarily bind strongly. Meaning that they don’t just bind these toxins and then never let them go.
Binders have different strengths for different toxins. They may bind some toxins more strongly and others more weakly.
Those that are bound more weakly can be dropped in the body where they end up circulating again. This is one way how binders can cause reactions for some people.
So, you want to go slow – only doing what you can tolerate.
And sometimes you may have to do just a little sprinkle of a binder once every other day, or every third day, and that’s okay.
Everyone must find their way through. This is why it can be good to work with a practitioner who can help you troubleshoot.
Next, let’s look at stage 6 of how to detox your body from mold – supporting detox pathways.
6. Supporting Needed Detox Pathways
Different types of mycotoxins are eliminated through different types of detox pathways.
You might have heard of glutathione. Glutathione is a detox pathway (called the glutathione pathway).
Glutathione is also a substance that gets made in the glutathione pathway. And it’s also a supplement.
Here, I’m talking about the pathway.
The glutathione pathway does work for a few mold toxins like Aflatoxin B1 and Ochratoxin. However, it’s not the primary detoxification method for most mold toxins.
Most mold toxins are detoxed via a pathway called glucuronidation.
Glucuronidation is the detox pathway for these mold toxins:
- Mycophenolic acid
- Roridin E
- T-2 Trichothecenes
- Verrucarin A
And then there are some more minor detox pathways that may be involved as well. Here are some of the other detox pathways:
- Amino acid conjugation
There are other minor detox pathways, too. But because glucuronidation is the most common detox pathway for mold toxins, I’ll just focus on that for now.
I like to support glucuronidation with:
It may help increase glucuronidation. It needs to be used cautiously in people who have low estrogen and have hot flashes.
If you do start to have hot flashes, it’s important to lower the dose because it can also bind estrogen.
It can increase an enzyme that’s involved in glucuronidation. It also increases antioxidants in the body to fight inflammation and other important detox pathways.
It may increase an enzyme that’s involved in glucuronidation. It also increases antioxidants in the body to fight inflammation.
It may help increase glucuronidation activity. It also has strong anti-inflammatory activity.
These have all been shown in published research to be helpful with glucuronidation.
Again, be sure to work with your healthcare practitioner on all this.
Some people just have mold toxins. They don’t have Mold Colonization.
Mold colonization is where mold is actually growing inside you.
If you just have mold toxins, you will likely feel dramatically different with just binders and a little detox support.
If that’s the case, then antifungals aren’t needed.
But if you don’t feel significantly better at this point, you may need to work with your health care practitioners on this last phase. It’s possible you have Mold Colonization, too.
If that’s the case, you may need to bring in antifungals.
There’s a reason you want to do this after you’ve gone through the previous stages. Once you start taking the antifungals, they will start killing off any kind of mold colonized in your body.
You want to be sure your body is prepared to handle that die-off.
Remember how we talked about “taking out the trash”? You want to be sure your body is set to collect the trash (toxins) and that the trash collector is coming (good elimination/addressing constipation).
A great starting point to consider is Argentyn 23.
This is a form of nanoparticle silver. It’s also been effective against molds, viruses, and bacteria.
It’s very important to use a nano particle silver like Argentyn 23, rather than a colloidal silver. You want smaller particle sizes, so they don’t accumulate in the body. If they accumulate in the body, you could end up with Silver Toxicity.
Most people start with a single drop 1x/day and very slowly work up to 1/8 tsp 2x/day and eventually ½ tsp 2x/day.
I know we’ve covered a lot on how to detox your body from mold. Just remember, take your healing one step at a time. And make sure those steps are in the right order!
Why You Should Work with a Mold/Mast Cell Specialist if you have Mold Toxicity and Mast Cell Activation Syndrome
As I’ve emphasized throughout this article, detoxing mold is something you may find you need help with.
Any type of detoxification is going to need to be done slowly so that your body doesn’t overreact. You want to release the stored toxins just a little bit at a time.
Overwhelming your body with too much mycotoxin release all at once is just going to cause more Mast Cell Activation.
This is something that needs to be done with a personalized, precision detox plan.
And remember, if you need help, please seek out a Mold/Mast Cell Specialist you trust to help you through the phases of detox and keep your body in balance along the way!
And remember, everyone’s healing process is different. I often get asked how long it will take to detox.
Generally, when you’re thinking about the timeline for mold detoxification, it’s dependent on a few things:
- How much you have going on – do you have co-infections, how is your overall toxic load, etc.
- How much exposure there’s been – how long were you exposed, how many types of mycotoxins are present in your system
- How sensitive you are – can you tolerate supplements
You’re looking at anywhere from 6-12 months on the short end and 2-3 years on average – depending on the factors listed above.
Most people, though, feel better as they go along.
So, just take it day by day. Each step in the right direction is one step closer to getting your life back from Mold Toxicity!
If you suspect you have Mold Toxicity, I suggest you check out my MC360TM Precision Mold Master Class.
I have a basic option that will empower any patient and an advanced practitioner level for those who want to dig into the research of their root causes.
Have you detoxed from Mold Toxicity? Tell us in the comments: What did you try and how did it go?
Read More on How To Detox Your Body From Mold
- Why is Mold Toxicity Such a Big Trigger of Mast Cell Activation Syndrome?
- Top 7 Home Mold Testing Mistakes – What to know when you have Mast Cell Activation Syndrome or Mold Toxicity
- Top Signs You Have Mold Toxicity – What to know for people with Mast Cell Activation Syndrome and Histamine Intolerance
- Testing Mycotoxins and Mold: One of the Biggest Root Triggers for Mast Cell Activation & Histamine Intolerance
- Is Sauna Safe in Mast Cell Activation Syndrome and Histamine Intolerance?
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